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Toxys is a Dutch biotech company that provides innovative in vitro toxicity screening solutions to rapidly identify hazardous and potential carcinogenic properties of novel compounds during the early phases of product and drug development.

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Publications

Paula van Rossum

Poster together with P&G presented at the SOT 2017: use of multiparametric mode of action approaches for genetic toxicity assessment

This poster describes the investigation of several different predictive, animal-free genetic toxicology methodologies with varying degrees of complexity. The predictive capacity of these methods was compared by testing 22 chemicals that represent a mix of DNA reactive chemicals, chemicals with known, mixed or unknown modes...

Paula van Rossum

ToxTracker, the future for genotoxicity screening of nanoparticles

Many of the traditional genotoxicity test methods [e.g. unscheduled DNA synthesis assay, bacterial reverse mutation (Ames) test, etc.,] for determining the DNA damaging potential of chemical and biological compounds are not suitable for the evaluation of engineered nanomaterials (ENMs), due to a variety of methodological...

Giel Hendriks

ToxTracker assay in Gen Magazine

Check out our recent publication about the ToxTracker assay together with Millipore. The publication shows the the power of the ToxTracker reporter assay in combination with the Millipore Guava platform....

Giel Hendriks

Read our latest publication about the ToxTracker assay

Just before the end of 2015, our most recent scientific description and validation of the ToxTracker technology got accepted for publication by the journal Toxicological Sciences.The publication reports on the ToxTracker assay for mechanistic genotoxicity screening. By utilising a panel of reporter genes that are...

Giel Hendriks

New paper ToxTracker and nanoparticles

 Check out our latest publication on how our stem cell-based ToxTracker reporter assay can provide insight in the mechanisms of toxicity of nanoparticles, meeting the urgent demands for better in vitro assays for toxicity testing of nanomaterials.Read abstract...