
ToxProfiler webinar : A quantitative high throughput screening platform with a single-cell resolution
08-04-2021
Date: April 8, 2021
Time: 7AM PDT | 10AM EDT | 4PM CEST
Presenter: Dr. Giel Hendriks, CEO of Toxys and Dr. Bas ter Braak, Senior Scientist at Toxys
ToxProfiler™ is a human cell reporter assay that can accurately quantify the cellular stress responses induced by chemicals. Each of the 7 ToxProfiler cell lines contains a specific fluorescent reporter that is associated with a cellular stress response pathway. ToxProfiler can be applied for broad toxicity profiling of compounds. During this webinar, we will demonstrate the applicability of the assay and share some use cases.
During this webinar you will also learn how the ToxProfiler assay:
- Generates a toxicological fingerprint for each compound
- Identifies the cellular stress responses that are activated upon exposure to compound
- Can be applied for early chemical safety testing and for investigating the toxic MoA of compounds.
- Support chemical read-across, perform potency ranking of compound series and calculate point-of-departure concentrations.