Consultants Symposium: Application of NAMs in chemical safety assessment

Consultants Day image

Consultants Symposium: Application of NAMs in chemical safety assessment

Consultants Day image

Consultants Symposium: Application of NAMs in chemical safety assessment

When: 27 March 3.00-5.00 pm CET
Register: click here

Within toxicology there are often well-defined strategies for evaluating the safety of novel chemicals and pharmaceuticals. In most cases, safety assessment still heavily relies on animal testing. However, there is a growing realization within both industry and health authorities that we need to modernize the way we assess the safety of compounds. In expert working groups within EMA, ECHA, FDA, HESI, and national health authorities there are ongoing evaluations to adopt NAMs (New Approach Methods) in the current chemical safety testing strategies.

At Toxys we have developed an extensive portfolio of NAMs for accurately predicting the toxicity of compounds and elucidating their toxic mode-of-action (MOA). Our assays primarily focus on genetic toxicology, developmental toxicity and mechanistic toxicity testing. These assays are frequently used by large pharma, cosmetics, consumer product, and (agro)chemical companies, with data being submitted to support regulatory applications. For ToxTracker, our genotoxicity assay, a large interlaboratory validation was completed and is currently under review by OECD. The ToxTracker assay is widely adopted by industry and results are being included in regulatory submissions. Also, our ReproTracker for developmental toxicity and ToxProfiler for mechanistic toxicity testing are widely being used and companies are building experience with these NAMs and integrate their data into the standard testing strategies.

In conversations with various consultants, a frequent question that came up was “How to best apply NAMs in a toxicity testing strategy? For this reason we are organizing a ”NAMs workshop”. During this online symposium, we will share in-depth information on our NAMs portfolio and actual use cases. Additionally, 2 independent consultants will share how they have advised and successfully used Toxys’ technology for their customers’ projects. Please join us!

Presentations:

Giel Hendriks – Toxys
Overview on ToxTracker, ReproTracker and ToxProfiler and some of their use cases

Sanghamitra Mishra – consultant at ToxMinds
A NAM-focused human health testing approach to meet the requirements of EU REACH registration and cosmetic safety assessment

Claudia Cusan – consultant at S&C Best Srl
Toxtracker applications in medical devices and chemical fields: examples from industry

During this seminar you will learn:

  • About our unique NAMs portfolio for genotoxicity, developmental toxicity and mechanistic toxicity testing
  • How these assays can be used and how it helped clients
Please click here to register
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