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Webinar: Applications of ToxProfiler for mechanistic toxicity profiling
On the 27th of June, we hosted a webinar entitled "Applications of ToxProfiler for mechanistic toxicity profiling". During this webinar, we introduces an exciting new extension of this assay, ToxProfiler MAX, and shared some case studies on ToxProfiler. Please click here to request the webinar from...
Join us at our ToxTracker hands-on training workshop!
[vc_row][vc_column][vc_column_text] Dates: 12 - 13 October 2023 Venue: Toxys B.V., De Limes 7, Oegstgeest, The Netherlands 2342 DH Join us for a hands-on training workshop on ToxTracker! ToxTracker is a unique genotoxicity assay that can reliably identify genotoxic compounds and can provide detailed insight into their mode-of-action. During the...
Integration and application of new approach methodologies in assessing the developmental hazards: Case study with an antimalarial drug
Check out this publication in which ReproTracker was utilized by Medicines for Malaria Venture (MMV) to verify the teratogenicity potential of an antimalarial agent and address the interspecies differences. Their study demonstrated that the use of NAMs, such as ReproTracker, can be helpful in understanding the...
Webinar: Application of ReproTracker in assessing developmental toxicity according to ICH S5
On the 12th of June, we hosted a webinar entitled "Application of ReproTracker in assessing developmental toxicity according to ICH S5". During this webinar, we showcased how ReproTracker fits in as an alternative assay under ICH S5 (R3) guidelines and highlight a few cases that...
Webinar: ToxTracker: Better Product Risk Assessment Results
Recently, Labstat International Inc. hosted a webinar on how the ToxTracker® genotoxicity assay can streamline nicotine product development. You can learn about how ToxTracker compares to other current tests and case studies from the nicotine industry by accessing the recording of the webinar here. About ToxTracker ToxTracker...
Labstat Inc., a Certified Group Company, partners with Toxys to offer the ToxTracker® assay
[vc_row][vc_column][vc_column_text] TORONTO, March 15, 2023 – Labstat Inc., A Certified Group Company, has entered into a partnership with Toxys to offer the ToxTracker assay at its Kitchener, Ontario laboratory. ToxTracker is a state-of-the-art stem cell-based reporter assay that provides mechanistic insights into the mode of action...
IIVS and Toxys enter into agreement to offer ToxTracker® for in vitro genetic toxicity evaluation
[vc_row][vc_column][vc_column_text] IIVS will offer ToxTracker®, expanding its portfolio of animal-free genetic toxicology assays Gaithersburg, M.D., USA, and Oegstgeest, The Netherlands, March 9, 2023 – The Institute for In Vitro Sciences (IIVS) and Toxys have entered into a license agreement that allows IIVS to offer the ToxTracker® assay....
Quantitative in vitro to in vivo extrapolation of genotoxicity data provides protective estimates of in vivo dose
Check out this recent publication by the Genetic Toxicology Technical Committee (GTTC) on in vitro to in vivo extrapolation (IVIVE) for genotoxicity. In vitro genotoxicity assays, including ToxTracker, were able to reliably predict in vivo genotoxicity from animal studies. Please click here to read the full...
Chemical and in vitro toxicological comparison of emissions from a heated tobacco product and the 1R6F reference cigarette
It has previously been found that, compared with cigarette smoke, the aerosols generated by heated tobacco products contain fewer and lower harmful and potentially harmful constituents (HPHCs) and elicit lower biological activity in in vitro models and lower smoking-related exposure biomarker levels in clinical studies. Here,...
Utility of ToxTracker in animal alternative testing strategy for fragrance materials
Check out this new paper by RIFM, P&G, and Toxys on how ToxTracker can be applied for testing fragrance materials. In an evaluation combining different genotoxicity assays, ToxTracker was a valuable tool for identifying the genotoxic potential of fragrances along with the mechanisms of action....
