How to Address Unexpected Genotoxicity Signals in Safety Testing of Medical Devices
[vc_row][vc_column width="2/3"][vc_column_text]As outlined in the updated ISO 10993 standards, genotoxicity assessment is becoming increasingly important in the biological evaluation of medical devices. Now, genotoxicity assessment is not only required for long-term contact devices, but also for less invasive devices with prolonged contact. Traditional genotoxicity testing strategies...
A Wide Range of Solvents that can be Used in the ToxTracker Genotoxicity Assay
[vc_row][vc_column][vc_column_text]When testing novel active pharmaceutical ingredients (API) for their genotoxic properties in early phases of drug development, it is not always possible to avoid residual solvent in the formulation. These solvent residues can lead to misleading genotoxicity results that are unrelated to the API. To...
ESTIV 2026 Highlights: Advancing NAMs Through Collaboration
[vc_row][vc_column][vc_column_text]ESTIV 2026 brought together researchers, regulators and industry experts from across the toxicology community to discuss the future of New Approach Methodologies (NAMs), with regulatory validation and implementation as central themes throughout the conference. Across scientific sessions, one message stood out: the field is rapidly progressing...
Working at Toxys as a BD & Sales Manager
[vc_row css=".vc_custom_1727793192295{padding-top: 2% !important;padding-right: 2% !important;padding-bottom: 2% !important;padding-left: 2% !important;}"][vc_column width="1/4"][vc_single_image image="15449" img_size="full" alignment="center"][/vc_column][vc_column width="3/4"][vc_column_text]Name: Katarina Spencer Role: Business Development and Sales Manager With Toxys since: 2024 Background: Genetics From: South Africa[/vc_column_text][/vc_column][/vc_row][vc_row][vc_column][vc_column_text] Can you give us a brief description of your role at Toxys? My overarching role is to act as...
Working at Toxys as a Study Investigator
[vc_row css=".vc_custom_1727793192295{padding-top: 2% !important;padding-right: 2% !important;padding-bottom: 2% !important;padding-left: 2% !important;}"][vc_column width="1/4"][vc_single_image image="15444" img_size="full" alignment="center"][/vc_column][vc_column width="3/4"][vc_column_text]Name: Eva de Tombe Role: Study investigator in investigative toxicology team With Toxys since: 2023 Background: Bio-Pharmaceutical Sciences From: The Netherlands[/vc_column_text][/vc_column][/vc_row][vc_row][vc_column][vc_column_text] Can you give us a brief description of your role at Toxys? I am responsible for...
Working at Toxys Inc. as a Director of BD & Sales
[vc_row css=".vc_custom_1727793192295{padding-top: 2% !important;padding-right: 2% !important;padding-bottom: 2% !important;padding-left: 2% !important;}"][vc_column width="1/4"][vc_single_image image="15354" img_size="full" alignment="center"][/vc_column][vc_column width="3/4"][vc_column_text]Name: Daniel J Roberts Role: Director BD & Sales With Toxys since: 2022 Background: Toxicology From: USA[/vc_column_text][/vc_column][/vc_row][vc_row][vc_column][vc_column_text] Can you give us a brief description of your role at Toxys? Stationed in the USA, my primary responsibility is...
NAMs to the rescue: developmental toxicity of PROTACs
[vc_row][vc_column width="2/3"][vc_column_text]Targeted protein degradation is an emerging therapeutic approach to target "undruggable" diseases that cannot be treated with traditional small molecules. Proteolysis-targeting chimeras (PROTACs) and molecular glue degraders (MGDs) leverage the natural process of protein degradation to remove disease-related proteins. A major challenge with PROTACs and...
ReproTracker in Charles River Blog
[vc_row][vc_column][vc_column_text]Eureka, the science blog of Charles River, recently published articles on ReproTracker. You can access the full articles by clicking on the images below each summary.[/vc_column_text][/vc_column][/vc_row][vc_row css=".vc_custom_1760443128555{margin-top: 20px !important;}"][vc_column width="1/2"][vc_column_text] Toxys ReproTracker 13 January 2025 In this blog based on an interview with our CEO, Giel Hendriks you...
Working at Toxys as a Study Investigator
[vc_row css=".vc_custom_1727793192295{padding-top: 2% !important;padding-right: 2% !important;padding-bottom: 2% !important;padding-left: 2% !important;}"][vc_column width="1/4"][vc_single_image image="15270" img_size="full" alignment="center"][/vc_column][vc_column width="3/4"][vc_column_text]Name: Mathyn Rijkers Role: Study Investigator in genetic toxicology team With Toxys since: 2022 Background: Toxicology and Environmental Health From: The Netherlands[/vc_column_text][/vc_column][/vc_row][vc_row][vc_column][vc_column_text] Can you give us a brief description of your role at Toxys? In our team...
Working at Toxys as a Scientist and Study Director
[vc_row css=".vc_custom_1727793192295{padding-top: 2% !important;padding-right: 2% !important;padding-bottom: 2% !important;padding-left: 2% !important;}"][vc_column width="1/4"][vc_single_image image="15195" img_size="full" alignment="center"][/vc_column][vc_column width="3/4"][vc_column_text]Name: Marit Hoogenboom-Geijer Role: Scientist for genetic toxicology R&D and Study Director for MutaTracker With Toxys since: 2020 Background: Biomedical sciences From: The Netherlands[/vc_column_text][/vc_column][/vc_row][vc_row][vc_column][vc_column_text] Can you give us a brief description of your role at Toxys? I...
