Industry Hosted Session
During this session, we will share about NAMs in the field of genetic, developmental, and investigative toxicology. We will share steps towards regulatory acceptance and how the assays are currently being used (application cases).
Session IHS04
Monday 15 Sep, 12:00-13:00
Room MC 2
Presentations:
- NAMs for genetic, developmental, and investigative toxicology | Paula van Rossum, Chief Business Officer at Toxys
- ToxProfiler updates: enabling mechanistic, animal-free toxicity testing with improved throughput and efficiency | Tamara Meijer, Study Director Investigative Toxicology at Toxys
- ToxTracker applications in medical devices and chemical fields: examples from industry | Dr. Claudia Cusan, European Registered Toxicologist and Vice-President at S&C BEST Srl
- Genotoxicity assessment of complex molecules: ToxTracker assay for synthetic organic dyes – Bringing mechanistic insights into regulatory requests | Dr. Giulia Martina Sitzia, Junior Regulatory Toxicologist at KAHLBERG Consulting
Resource Download Packages
After filling in the form, you will receive the resource links into your inbox. Just tick boxes of your interest.
Resources in EUROTOX 2025 Congress packages are as below.
Genetic Toxicology Package
- Flyer: 1) ToxTracker Suite 2) MutaTracker 3) About Toxys
- Publication: 1) Interlaboratory validation of the ToxTracker assay: An in vitro reporter assay for mechanistic genotoxicity assessment 2) Critical Evaluation of Methods for the Identification of Aneugens 3) The Extended ToxTracker Assay Discriminates Between Induction of DNA Damage, Oxidative Stress, and Protein Misfolding
- Webinar: Validation of ToxTracker for Regulatory Genetox Testing Strategies
- Case study: Can ToxTracker replace the in vitro micronucleus test?
- Other: Press release – ToxTracker® Approved by OECD for Incorporation into Test Guideline Programme
Download this package.
Or download all 3 packages.
Developmental Toxicology Package
- Poster: Evaluating the potential of ReproTracker as an alternative assay for regulatory use following the ICH S5 (R3) guideline
- Flyer: 1) ReproTracker 2) About Toxys
- Publication: A novel human stem cell-based biomarker assay for in vitro assessment of developmental toxicity
- Webinar: Application of ReproTracker in assessing developmental toxicity according to ICH S5
- Case study: 1) Biology matters! Early teratogenicity assessments using ReproTracker 2) NAMs to the rescue: developmental toxicity of PROTACs
Download this package.
Or download all 3 packages.
Investigative Toxicology Package
- Poster: Read-across analysis of conazoles using ToxProfiler: Insights from the RISK-HUNT3R case study
- Flyer: 1) ToxProfiler 2) ToxProfiler MAX 3) About Toxys
- Publication: ToxProfiler: A novel human-based reporter assay for in vitro chemical safety assessment
- Case study: Can ToxProfiler guide DILI predictions?
Download this package.
Or download all 3 packages.
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Presentations
Evaluating the potential of ReproTracker as an alternative assay for regulatory use following the ICH S5 (R3) guideline
Poster Viewing III (PV03), Topic P28 | Reproductive and developmental toxicology, Poster # P28-08
Paula van Rossum (CBO at Toxys)
Read-across analysis of conazoles using ToxProfiler: Insights from the RISK-HUNT3R case study
Poster Viewing III (PV03), Topic P30 | Risk Prediction and Assessment /Risk assessment using New Approach Methodologies, Poster # P30-48
Tamara Meijer (Study Director Investigative Toxicology at Toxys)
Presentations by others with Toxys assays:
- S03-04 – Induction of genomic damage by natural plant constituents: development of genotoxicity testing strategies (#26). Helga Stopper – Professor at Julius Maximilians University of Würzburg
- P27-35 – Propyl Gallate Genotoxicity: Reliable Assessment through NAMs and In Vivo Testing Strategies (#1283). Jennifer Kurzke – Senior Consultant at Ramboll
- P21-01 – Assessment of a range of Next Generation Nicotine products using ToxTracker® and ToxProfilerᵀᴹ MAX assays reveal marked reductions in biological activity compared to a cigarette (#199). Matthew Stevenson – Scientific Substantiation Senior Manager at Imperial Brands
- P30-11 – Assessment of Disposable of e-vapour products using New Approach Methodologies shows marked reductions in toxicity relative to a cigarette (#270). Ourania Komini – NGP Science Manager at Imperial Brands
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Team on Location
Paula van Rossum
CBO
Tamara Meijer
Study Director Investigative Toxicology
Hanna Frykman
Director BD & Sales
Katarina Spencer
Manager BD & Sales
Would you like to have a 1-1 meeting?
Reserve a time slot here.
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