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ToxTracker included in webinar by Charles River: Avoid Program Set-Backs: Deciphering Positive Reponses
In a webinar on genetic toxicology by Charles River the ToxTracker assay was included. Via this link you can view the webinar, the information on ToxTracker starts at 38 minutes. ...
Toxys is part of organising committee for workshop: Mode of Action Approaches That Identify Genotoxic Mechanisms in Mammalian Cell Systems (May 10th 2017)
The HESI Genetic Toxicology Technical Committee (GTTC) will hold the workshop in conjunction with the Genetic Toxicology Association (GTA) annual meeting on 10 May 2017 in Newark, Delaware. The first part of the workshop is intended to establish key cellular and genetic events for defined...
Interview with Toxys CEO Giel Hendriks and cover spread in TerugbliQ – the year report from Innovation Quarter
In TerugbliQ, the year report from Innovation Quarter you can read an interview with our CEO Giel Hendriks (in Dutch), please click here for the year report and the interview...
Poster together with Concawe presented at the SOT 2017: Use of ToxTracker for Petrochemical products
The goal of this project was to investigate whether the ToxTracker assay can be applied to petroleum UVCBs as a high-content screen for mutagenicity / carcinogenicity by testing by testing twelve DMSO extracts of petroleum substances for (geno)toxic properties in the assay. Conclusions: The ToxTracker assay...
Poster together with P&G presented at the SOT 2017: use of multiparametric mode of action approaches for genetic toxicity assessment
This poster describes the investigation of several different predictive, animal-free genetic toxicology methodologies with varying degrees of complexity. The predictive capacity of these methods was compared by testing 22 chemicals that represent a mix of DNA reactive chemicals, chemicals with known, mixed or unknown modes...
Toxys mentioned as top-10 biotech in Leiden
In this article by Labiotech.eu Toxys is mentioned as one of the top-10 biotech companies in Leiden. Stroopwaffels, Krokets and Biotechs – Meet the Top 10 in Leiden! ...
ToxTracker – the better genotoxicity assay
This is the first blog in a series to come to share what we are doing at Toxys and to inspire you. Toxys provides innovative in vitro toxicity screening solutions to rapidly identify hazardous and potential carcinogenic properties of novel compounds during the early phases...
Toxys newsletter November 2016
Here you can view our newsletter for November 2016...
Toxys awarded € 50.000 by EIT Health to develop ReproTracker – an in vitro assay for reproductive toxicity
21 September 2016 - Today Toxys was awarded a €50.000 grant for a head-start project to further develop the ReproTracker. Toxys is dedicated to develop innovative in vitro toxicity assays that provide insight into the mechanisms of toxicity. Toxys' lead product ToxTracker is a genotoxicity...
ToxTracker, the future for genotoxicity screening of nanoparticles
Many of the traditional genotoxicity test methods [e.g. unscheduled DNA synthesis assay, bacterial reverse mutation (Ames) test, etc.,] for determining the DNA damaging potential of chemical and biological compounds are not suitable for the evaluation of engineered nanomaterials (ENMs), due to a variety of methodological...
Application note Millipore featuring the ToxTracker assay
Benchtop flow cytometry facilitates discrimintion between induction of DNA damage, oxidative stress and protein misfolding using a novel multicell GFP reporter assay. ...
ToxTracker suggested as part of “An integrative test strategy for cancer hazard”
A recent publication by the Dutch National Institute for Health and Environment (RIVM) reviews the current test methods for cancer hazard identification that have been adopted by the regulatory authorities and discusses the most promising alternative methods that have been developed to date. Based on...
Grand Opening new facilities Toxys
On the 26th of May Toxys organised a grand opening party. Over 50 people joined, among which were Innovation Quarter, the Leiden Bioscience Park, Biopartner and various entrepreneurs and collaborators. We are very happy with our new location and state-of-the-art equipment and look forwards to expanding...
ToxTracker assay in Gen Magazine
Check out our recent publication about the ToxTracker assay together with Millipore. The publication shows the the power of the ToxTracker reporter assay in combination with the Millipore Guava platform. ...
New Publication on how the ToxTracker assay provides mechanistic insight
Our latest publication about the development and validation of the ToxTracker assay is now available online. The paper describes the different fluorescent reporter cell lines that ar used in ToxTracker to gain insight into the mechanism of genotoxicity of compounds. The ToxTracker assay is a...
A Milestone for Toxys: Growth capital for biotech company Toxys to develop Toxicological tests
The Zeeuws Investment Fund and InnovationQuarter have invested in the biotech company Toxys, located in Leiden, The Netherlands. Toxys is a spin-off from the Leiden University Medical Centre (LUMC) and specialized in a new generation of innovative testing which quickly and reliably can identify the...
Read our latest publication about the ToxTracker assay
Just before the end of 2015, our most recent scientific description and validation of the ToxTracker technology got accepted for publication by the journal Toxicological Sciences. The publication reports on the ToxTracker assay for mechanistic genotoxicity screening. By utilising a panel of reporter genes that are...
Toxys joins IVTIP
Toxys recently joined the In Vitro Testing Industrial Platform (IVTIP). IVTIP is an informal platform that was founded in 1993 and currently comprises 42 companies from different sectors (assay developers, technology providers, chemical, pharmaceutical and cosmetics companies), with significant in vitro testing activities. Most of the...
