Publications on our technology

An overview of our essential publications on the technology behind assays from Toxys is available here. Please click on the publications to request an author’s copy.

The ToxTracker assay: novel GFP reporter systems that provide mechanistic insight into the genotoxic properties of chemicals

Hendriks, G., et al. (2012), Toxicological Sciences

The Extended ToxTracker Assay Discriminates Between Induction of DNA Damage, Oxidative Stress, and Protein Misfolding

Hendriks, G., et al. (2016), Toxicological Sciences

Aneugen Versus Clastogen Evaluation and Oxidative Stress-Related Mode-of-Action Assessment of Genotoxic Compounds Using the ToxTracker Reporter Assay

Brandsma, I., et al. (2020), Toxicological Sciences

TubulinTracker, a Novel In Vitro Reporter Assay to Study Intracellular Microtubule Dynamics, Cell Cycle Progression, and Aneugenicity

Geijer, M. E., et al. (2022), Toxicological Sciences

A novel human stem cell-based biomarker assay for in vitro assessment of developmental toxicity

Jamalpoor A. et al. (2022), Birth Defects Research

Quantitative interpretation of ToxTracker dose-response data for potency comparisons and mode-of-action determination

Boisvert L. et al. (2023), Environmental and Molecular Mutagenesis