Scientific Advisory Board

Bob van de Water

Bob van de Water received his PhD in 1995 from Leiden University. He is a professor in Drug Safety Sciences at the Leiden Academic Centre for Drug Research (LACDR) at Leiden University and head of the Division of Drug Discovery and Safety. He has worked on molecular mechanisms of toxicity for over 30 years. This work led to the development of fluorescent protein reporter platforms to quantify cellular stress responses in relation to chemical and drug exposure and qualify the liability for adverse responses. He currently is the coordinator of the EU-ToxRisk project that worked on integrated testing strategies for read-across applying new approach methodologies. He also coordinates the recently funded RISK-HUNT3R project that will focus on next-generation risk testing strategies.

Clive Roper

Clive Roper holds a PhD in in vitro dermal toxicology from Newcastle University. From 1996 to 2021, he worked at Charles River, progressing to Director, in vitro toxicology responsible for skin absorption, regulatory in vitro toxicology, genetox, safety pharmacology, and in vitro respiratory toxicology. He has developed models resulting in the direct replacement of animals in dermal absorption, dermal toxicology and inhalation toxicology. He is a member of the North American 3Rs Collaborative and serves on the microphysiology (MPS) subgroup and is also a member of the Board of the UK NC3Rs. In 2021, Clive set up his consulting business, Roper Toxicology Consulting Limited, aiding in the development of new approach methodologies with SMEs and supporting regulatory acceptance of products to market.

Peter Boogaard

Peter Boogaard holds degrees in both pharmacy and chem­istry, and a PhD in Toxicology from Leiden University. He is the Professor of Environmental Health and Human Biomonitoring at the Division of Toxicology of Wageningen University and he has served on several committees of the Health Council of The Netherlands. Peter has been the chair of the toxicology group of CONCAWE, a member of the scientific council of ECETOC, and other tripartite committees on chemicals risk assessment. He is a scientific advisor on Risk Assessment for the European Commission and served on the Scientific Committee for Occupational Exposure Limits. Peter is also a (co-)author of more than 300 scientific publications and reports, in the fields of occupational toxicology, NAMS, human biomonitoring, dermal exposure, reproductive toxicity, nephrotoxicity and (cancer) risk assessment.