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Paula van Rossum

ToxTracker event and launch party at SOT 2020

You are cordially invited to join the ToxTracker event and launch party during the SOT 2020 meeting in Anaheim. During this event we will launch new assays, software and the ToxTracker Academy. We will also update you on the latest developments around ToxTracker and its...

Paula van Rossum

Toxys strengthens leadership team with appointment of CBO and COO positions

Leiden, The Netherlands. Jan. 21, 2020 - Today, Toxys announces the appointment of a Chief Business Officer (CBO) and a Chief Operating Officer (COO). Toxys BV is a biotech company based in Leiden, The Netherlands, that provides innovative, high-fidelity in vitro toxicity screening solutions to identify carcinogenic and other hazardous properties...

Paula van Rossum

ToxTracker for regulatory applications

We are frequently asked whether ToxTracker data have ever been included in safety dossiers to the regulatory authorities. The answer is yes, but often this information is not publicly available. And in many cases we simply don’t know. But now there is an example available...

Paula van Rossum

Greatly improved metabolising system for ToxTracker

5 July 2018 - ToxTracker is an in vitro assay that provides detailed insight into the mode-of-action of genotoxic compounds. The assay is generally performed in the absence and presence of a metabolising system. Metabolic activation of compounds is included following the industry standard by...

Paula van Rossum

Collaboration with Health Canada and University of Swansea to implement quantitative analysis of ToxTracker results for human risk assessment

Toxys has started a collaboration with Health Canada and the University of Swansea to implement the Quantitative Analysis tool PROAST for ToxTracker results. There is growing interest in quantitative analysis of in vitro genetic toxicity dose‐response data, and use of point‐of‐departure (PoD) metrics such as the...

Giel Hendriks

Read our latest publication about the ToxTracker assay

Just before the end of 2015, our most recent scientific description and validation of the ToxTracker technology got accepted for publication by the journal Toxicological Sciences. The publication reports on the ToxTracker assay for mechanistic genotoxicity screening. By utilising a panel of reporter genes that are...