Latest publication about aneugen versus clastogen evaluation and oxidative stress-related MOA
Check out our latest publication “Aneugen versus clastogen evaluation and oxidative stress-related mode-of-action assessment of genotoxic compounds using the ToxTracker reporter assay” published recently in Toxicological Sciences.
This paper highlights the extended versions of the ToxTracker assay: ToxTracker ACE and ToxTracker AO. ToxTracker ACE (Aneugen Clastogen Evaluation) discriminates between aneugenic and clastogenic compounds. ToxTracker AO identifies indirect genotoxicity due to the formation of ROS. These extensions improve the overall sensitivity and specificity of the ToxTracker system for genotoxicity assessment.