- All
- Blog
- Grants
- News
- Newsletter
- Press Release
- Publications
- Uncategorized
- Webinar
New Publication: Critical Evaluation of Methods for the Identification of Aneugens
[vc_row][vc_column][vc_column_text]As a member of HESI’s Genetic Toxicology Testing Committee (GTTC), we co-published an article in Environmental and Molecular Mutagenesis entitled “Critical Evaluation of Methods for the Identification of Aneugens”. This article presents the strengths, weaknesses, opportunities, and threats for a variety of technologies currently being...
Toxys CEO Giel Hendriks becomes EEMGS Vice President
[vc_row][vc_column][vc_column_text]Toxys CEO Giel Hendriks was announced as the new Vice President of the European Environmental Mutagenesis and Genomics Society (EEMGS) during the recent annual meeting of the society in Bratislava. Giel will fulfill this role for the next 2 years. As Toxys team, we are...
Working at Toxys Inc. as a Director of BD & Sales
[vc_row css=".vc_custom_1727793192295{padding-top: 2% !important;padding-right: 2% !important;padding-bottom: 2% !important;padding-left: 2% !important;}"][vc_column width="1/4"][vc_single_image image="15354" img_size="full" alignment="center"][/vc_column][vc_column width="3/4"][vc_column_text]Name: Daniel J Roberts Role: Director BD & Sales With Toxys since: 2022 Background: Toxicology From: USA[/vc_column_text][/vc_column][/vc_row][vc_row][vc_column][vc_column_text] Can you give us a brief description of your role at Toxys? Stationed in the USA, my primary responsibility is...
New publication: Genotoxicity testing of N-nitrosamines using mammalian cells
[vc_row][vc_column][vc_column_text]Toxys scientists recently published an article in Environmental and Molecular Mutagenesis entitled “An Enhanced Metabolization Protocol for In Vitro Genotoxicity Assessment of N-Nitrosamines in Mammalian Cells”. In this article, we established a proof of concept for an exogenous metabolization protocol that activates N-nitrosamines (NAs) and...
Towards quantitative genotoxicity assessment: ToxTracker reporting will include BMD Analysis
[vc_row][vc_column][vc_column_text]For hazard identification, a qualitative answer whether a substance is genotoxic or not is often sufficient. To use ToxTracker data for risk assessment, quantification of the dose response of a test substance will be required. Therefore, Toxys has incorporated benchmark dose (BMD) response modeling into...
Advancing Chemical Safety Testing Through NAMs!
[vc_row][vc_column][vc_column_text]We recently published an article entitled “Toxicological mode-of-action and developmental toxicity of different carbon chain length PFAS” in Toxicology Letters together with Honeywell. We utilized two of our advanced assays, ToxProfiler and ReproTracker, to assess the toxicological mode-of-action and developmental toxicity of different PFAS with varying...
NAMs to the rescue: developmental toxicity of PROTACs
[vc_row][vc_column width="2/3"][vc_column_text]Targeted protein degradation is an emerging therapeutic approach to target "undruggable" diseases that cannot be treated with traditional small molecules. Proteolysis-targeting chimeras (PROTACs) and molecular glue degraders (MGDs) leverage the natural process of protein degradation to remove disease-related proteins. A major challenge with PROTACs and...
ReproTracker in Charles River Blog
[vc_row][vc_column][vc_column_text]Eureka, the science blog of Charles River, recently published articles on ReproTracker. You can access the full articles by clicking on the images below each summary.[/vc_column_text][/vc_column][/vc_row][vc_row css=".vc_custom_1760443128555{margin-top: 20px !important;}"][vc_column width="1/2"][vc_column_text] Toxys ReproTracker 13 January 2025 In this blog based on an interview with our CEO, Giel Hendriks you...
Toxys Awarded £1M for phase 2 of CrossDART CRACK IT Challenge
To address the need for reliable cell based in vitro assays that predict the teratogenicity of new drug candidates in both human and other animal species, Toxys have participated in CrossDART CRACK IT Challenge, developing and characterizing muti-species assays. After successfully completing phase 1 of...
Toxys and Unilever to explore and develop new approach methods (NAMs) for cellular stress
[vc_row][vc_column][vc_column_text]Toxys and Unilever have signed a collaboration to explore New Approach Methodologies (NAMs) that can be used to provide insight into cellular stress, a key mode of action for consideration in Next Generation Risk Assessment (NGRA) without animal testing. This collaboration will include comparing existing...
