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Labstat Inc., a Certified Group Company, partners with Toxys to offer the ToxTracker® assay
[vc_row][vc_column][vc_column_text] TORONTO, March 15, 2023 – Labstat Inc., A Certified Group Company, has entered into a partnership with Toxys to offer the ToxTracker assay at its Kitchener, Ontario laboratory. ToxTracker is a state-of-the-art stem cell-based reporter assay that provides mechanistic insights into the mode of action...
IIVS and Toxys enter into agreement to offer ToxTracker® for in vitro genetic toxicity evaluation
[vc_row][vc_column][vc_column_text] IIVS will offer ToxTracker®, expanding its portfolio of animal-free genetic toxicology assays Gaithersburg, M.D., USA, and Oegstgeest, The Netherlands, March 9, 2023 – The Institute for In Vitro Sciences (IIVS) and Toxys have entered into a license agreement that allows IIVS to offer the ToxTracker® assay....
Quantitative in vitro to in vivo extrapolation of genotoxicity data provides protective estimates of in vivo dose
Check out this recent publication by the Genetic Toxicology Technical Committee (GTTC) on in vitro to in vivo extrapolation (IVIVE) for genotoxicity. In vitro genotoxicity assays, including ToxTracker, were able to reliably predict in vivo genotoxicity from animal studies. Please click here to read the full...
Chemical and in vitro toxicological comparison of emissions from a heated tobacco product and the 1R6F reference cigarette
It has previously been found that, compared with cigarette smoke, the aerosols generated by heated tobacco products contain fewer and lower harmful and potentially harmful constituents (HPHCs) and elicit lower biological activity in in vitro models and lower smoking-related exposure biomarker levels in clinical studies. Here,...
Utility of ToxTracker in animal alternative testing strategy for fragrance materials
Check out this new paper by RIFM, P&G, and Toxys on how ToxTracker can be applied for testing fragrance materials. In an evaluation combining different genotoxicity assays, ToxTracker was a valuable tool for identifying the genotoxic potential of fragrances along with the mechanisms of action....
Webinar: DNA Repair-Profiler, a new in vitro assay for DNA repair & genotoxic mode of action assessment
On the 31st of January, we hosted a webinar entitled "DNA Repair-Profiler, a new in vitro assay for DNA repair and genotoxic mode of action assessment". During this webinar, we introduced the latest assay to be added to our portfolio: DNA Repair-Profiler. Please click here to request...
Quantitative interpretation of ToxTracker dose-response data for potency comparisons and mode-of-action determination
Check out our latest publication about quantitative dose-response modeling for ToxTracker to improve the predictions for in vivo genotoxicity. We used the BMD approach to assess the mode-of-action of genotoxic compounds. This information can be highly valuable for regulatory applications. Please click here for the paper....
Cytotoxicity Mechanisms of Eight Major Herbicide Active Ingredients in Comparison to Their Commercial Formulations
Most research on plant protection products focuses on active ingredients, while co-formulants are generally considered non-toxic. To investigate the actual toxicity of these commercial formulations, S. Ferguson and colleagues at Kings College London researched 8 major herbicides using ToxTracker and several other assays. Click here to...
The ReproTracker team wins the EPAA Science Prize 2022!
We are very proud that Dr Amer Jamalpoor, study director of ReproTracker and lead scientist in developmental toxicology, was awarded the EPAA European Partnership for Alternatives Science Prize 2022 for outstanding contributions towards animal-alternative testing methods. The awarded case study, “ReproTracker: an animal-free platform for developmental...
Toxys is scaling up in the US
After establishing a Toxys subsidiary in the US last year, we are scaling up our business at Toxys Inc. We have hired a Director of BD & Sales to expand our commercial activities and officially started the production of our ToxTracker kits and reagents in...
